Ether was the first anesthesia to be used in surgery. Before it became available, surgery was a prospect that few people were willing to undergo.
“The inhalation of ether as a means of rendering patients unconscious of pain during surgical operations, was tried at the Stamford Infirmary on Wednesday the 17th inst. Two cases were subjected to the process, and the apparatus used was that invented by Professor Fergusson, of King’s College, London. The first patient was an agricultural labourer, 36 years of age, who that morning had had his hand crushed by a thrashing-machine, making it necessary that one of the fingers should be amputated. After he had inhaled the ether for three minutes and a half, he appeared to be under its influence, uttering a disagreeable moaning noise, his eyes being fixed, and his face livid. The operation was quickly performed. When it was over, he was asked whether he had been aware of what was going on? – to which he promptly repliee (sic), ‘Oh yes, I felt you all the while.’ – The second case was that of a young woman, one of whose teeth was to be drawn; and with her the effect of the ether was more quick and more complete, for in a minute and a half she was evidently unconscious, and the tooth was soon extracted. It then becamse necessary to use stimulants, and to dash cold water in her face to restore her. On her reviving, she was asked whether she would have the tooth drawn? to which she answered rather archly, ‘I think it is out.’ In this instance the effects of the ether did not go off so happily as had been hoped for; the girl continued in a comatose somnolent state till the Friday following, taking no notice of anything, but answering questions when put in a loud tone. Some active means being then used, she began to improve, and his now recovered her usual state of health. – From this case, we may infer that the propriety of using an agent so powerful as the ether inhalation in the minor operations of surgery is doubtful; for it is uncertain whether a greater evil may not be inflicted than is avoided by it.”
The Stamford Mercury, 26th February, 1847.